Kolicina HCG-a po nedeljama

Evo drage zene nadam da ce koristiti da se informisemo kolika kolicina HCG-a u krvi po nedeljama treba da bude.

Beta Scores for Successful* Single Pregnancies
Days Past Ovulation Median HCG LevelLowest HCG Level ReportedHighest HCG Level ReportedNumber of women reporting a number for this day

10	16	1	245	60
11	24	2	196	250
12	37	2	294	544
13	62	3	575	1034
14	101	3	2088	2108
15	136	3	2088	2717
16	200	5	9000	2949
17	291	5	9000	3030
18	405	7	10529	2882
19	598	16	12318	2731
20	840	28	14411	2462
21	1211	41	16860	2190
22	1668	58	19861	1849
23	2358	17	27000	1615
24	3321	144	28000	1342
25	4163	218	36984	1101
26	5501	290	41854	945
27	6971	351	41625	785
28	9287	429	58500	696
29	11357	440	73973	572
30	14687	539	131472	500

* Pregnancies are deemed successful if a heartbeat is detected.

* Pregnancies are deemed successful if a heartbeat is detected.

Podaci su sa sajta
http://www.betabase.info/index.php
Bice od koristi, svakako

BETA HCG

HCG is the abbreviation for "Human Chorionic
Gonadotropin". hCG is the "pregnancy
hormone" which is being produced by the placenta as soon as implantation
happens about one week after fertilization and ovulation. hCG then continues to
rise until about 10-12 weeks at which point it will stabilize or drop.

Many women wonder whether they have a normal hCG level or not.

There is really no single "normal" hCG level and there is a very wide
range of hCG values as pregnancy progresses.

If you are interested to find out if your pregnancy is progressing normally
or not then the most important information is to find out whether
your blood hCG level is rising normally or not.

1. Blood hCG testing is much
   more sensitive than a urine HPT. This means that the blood test can detect
   pregnancy several days earlier than the urine test, as early as 10 days
   after fertilization, 3-4 days after implantation.
   
2. hCG is measured in
   milli-international units per milliliter (mIU/ml).
   
3. Urine tests measure the
   urine HCG qualitatively, which means that the HPT results are either
   "positive" or "negative." Around the time of the first
   missed period (14+ days after ovulation), over 95% of HPTs are usually
   positive.
   
4. About 85% of normal pregnancies
   will have the hCG level double every 48 - 72 hours. As you get further
   along into pregnancy and the hCG level gets higher, the time it takes to
   double can increase to about every 96 hours.
   
5. Caution must be used in
   making too much of hCG numbers. A normal pregnancy may have low hCG levels
   and deliver a perfectly healthy baby.
   
6. The results on an
   ultrasound after 5 - 6 weeks gestation are much more accurate than using
   hCG numbers.
   
7. An hCG of less than 5
   mIU/cc is usually negative, over 25 mIU/cc usually positive, between 5 and
   25 mIU/cc it's "equivoval" which simply means we don't know.
   
8. A transvaginal ultrasound
   should be able to see at least a gestational sac once the hCG levels have
   reached between 1,000 - 2,000mIU/ml.
   
9. Because levels can
   differentiate so much and conception dating can be wrong, a diagnosis
   should not be made by ultrasound findings until the level has reached at
   least 2,000.
   
10. A single hCG reading is not
    enough information for most diagnoses. When there is a question regarding
    the health of the pregnancy, multiple testings of hCG done a couple of
    days apart give a more accurate look at assessing the situation.
    
11. hCG levels should not be
    used to date a pregnancy since these numbers can vary so widely.
    
12. There are two common types
    of hCG tests. A qualitative hCG test just looks to see if hCG is present
    in the blood. A quantitative hCG test (or beta hCG) measures the amount of
    hCG actually present in the blood.
    
13. Other than for the
    diagnosis of pregnancy, hCG is also often monitored over time for reasons
    such as monitoring after a miscarriage, monitoring an ectopic pregnancy,
    and after a condition called "H.mole."
    
14. The first detection of hCG
    in the blood depends on when implantation happens. Extremely sensitive
    tests which are not available in a regular laboratory can detect the hCG
    even before implantation. But with regular laboratory hCG tests, hCG is
    usually found in sufficient levels as early as 2-3 days after
    implantation.
    
15. Implantation happens as
    early as 6 days after ovulation/fertilization (usually about 9 days after
    ovulation), so blood hCG can be found as early as 8-9 days after
    ovulation/fertilization.
    
16. Pregnant women usually
    attain blood serum concentrations of at least 10-50 mIU/cc in the 7-8 days
    following implantation.
    
17. An equivocal test of
    between 5 and 25 mIU/cc requires a repeat within 2-3 days. If if goes
    higher then that's a good sign, but if it goes lower or stays about the
    same then that's a sign that the pregnancy has failed
    
18. HCG monitoring is useful to
    assess the pregnancy before the fetal heart is seen (before 6-7 weeks
    after LMP), ususally to rule out an ectopic pregnancy or an early
    miscarriage
    
19. In an ectopic pregnancy,
    hCG increases at lower rates than in a normal pregnancy
    
20. In a noviable pregnancy it
    also rises slower
    
21. At hCG levels above
    1,000-1,500 mIU/ml, vaginal sonography usually identifies the presence of
    an intrauterine pregnancy
    
22. Within the first 2-4 weeks
    after fertilization, hCG usually doubles every 48-72 hours
    
23. An increase of 60% in 48
    hours is still considered normal
    
24. Below 1,200 mIU/ml, hCG
    usually doubles every 48-72 hours
    
25. Between 1,200 and 6,000
    mIU/ml serum, the hCG usually takes 72-96 hours to double
    
26. Above 6,000 mIU/ml, the hCG
    often takes over four days to double
    
27. More than two in three
    normal pregnancies have a doubling of the hCG every 72 hours
    
28. There is a wide variation
    of normal hCG levels. An hCG that does not double every two to three days
    does not necessarily indicate a problem
    
29. A maximum level is usually
    reached by the 10th or 11th week.
    
30. After 10 weeks or so, hCG
    normally decreases
    
31. Normal hCG values vary up
    to 20 times between different pregnancies
    
32. A single hCG value doesn't
    give enough information about the viability of the pregnancy
    
33. Pregnancies that will
    miscarry and ectopic (tubal) pregnancies are likely to show lower levels
    and slower rises, but often have normal levels initially
    
34. Some normal pregnancies
    will have quite low levels of hCG -- and deliver perfect babies
    
35. Once fetal activity has
    been detected by ultrasound in a normal patient population, chances of
    normal delivery are about 95%
    
36. Normal levels of hCG can
    vary tremendously. After 5-6 weeks of pregnancy, sonogram findings are
    much more predictive of pregnancy outcome than are HCG levels. Once the
    fetal heart rate is seen, most doctors will monitor the fetal heart rate
    rather than drawing hCG
    
37. After hCG injections
    (Profasi, Pregnyl) to trigger ovulation or to lengthen the luteal phase,
    trace amounts of hCG can remain in the body as long as 14 days or longer
    after the last hCG injection. This may give a false positive on a
    pregnancy test.
    
38. Two consecutive
    quantitative hCG beta blood tests can determine whether the hCG is from an
    injection or pregnancy. If the hCG level increases by the second test, you
    are likely pregnant
    

Preuzeto sa Roda.hr



Hormon trudnoće i njegovo dupliranje



HCG
(humani korionski gonadotropin) je glikoprotein kojeg izlučuje sloj
stanica s vanjske strane oplođene jajne stanice ili sinciciotrofoblast.
Najvažnija funkcija HCG-a je poticanje žutog tijela u jajniku da u
prvih 7-9 tjedana trudnoće luči progesteron, hormon znan i kao "čuvar
trudnoće".











Njegov nalaz, odnosno nalaz jednog njegovog dijela tzv. beta lanca
ili beta HCG-a može se naći u krvi i urinu trudne žene 1-2 dana nakon
ugnježđivanja, odnosno 8-10 dana nakon ovulacije. Njegova vrijednost
stalno progresivno raste sve do kraja prvog tromjesječja kada ulogu
proizvodnje progesterona preuzima posteljica a njegova vrijednost
počinje opadati. Tada se i mučnine, koje više-manje osjeća večina
trudnica, povlače. Razlog tome može biti što korionski gonadotropin
djeluje na hipotalamus (dio mozga koji nadzire vegetativni živčani
sustav) i na rinencefalon – moždani centar zadužen za opažanje i
raspoznavanje mirisa. Vjerojatno je to razlog što neki okusi i mirisi
iznenada postaju odbojni, te mogu izazvati mučninu i povraćanje.
U vrijeme očekivane menstruacije (obično 12-14 dana nakon ovulacije)
vrijednost beta HCG-a iznosi oko 100,0 IU/L. Jednostavni urinski
testovi već reagiraju na vrijednosti HCG-a od 25 IU/L (osjetljivost
urinskog testa provjerite u uputama za upotrebu ili upitom u ljekarni)
što znači da u vrijeme očekivane menstruacije, kada su očekivane
vrijednosti puno veće, točnost ovog jednostavog testa te osjetljivosti
iznosi oko 99%.
Ženama koje su primale HCG injekcije (Profasi i sl.) kao dio
tretmana liječenja neplodnosti treba oko 5 -14 dana da se HCG «očisti»
iz organizma, te mogu dobiti lažno pozitivan retultat ako ga rade prije
navedenog vremena.
Dok nam urinski test može pokazati samo je li HCG prisutan ili ne,
kvantitativni beta HCG test krvi može nam reći puno više. Praćenje
vrijednosti beta HCG-a je vrlo važna dijagnostička metoda u ocjeni
vijabilnosti ploda, dijagnostici izvanmaterične trudnoće, mole
hidatidoze, tumora jajnika ili testisa i sl. Naime HCG, osim u
trudnoći, može se pojaviti i kod nekih bolesti kako kod žena, tako i
kod muškaraca.
U sljedećoj tablici prikazana je prosječna očekivana količina HCG-a po tjednima trudnoće:

Tjedan nakon prvog dana posljednje menstruacije	Količina HCG-a (mIU/ml)
3	5 -50
4	3 – 426
5	19 - 7,340
6	1,080 - 56,500
7 – 8	7,650 - 229,000
9 – 12	25,700 - 288,000
13 – 16	13,300 - 254,000
17 – 24	4,060 - 165,400
25 – 40	3,640 - 117,000

Iz tablica primjećujemo da postoji široki spektar normalnih
vrijednosti, te pojedinačni nalaz HCG vrijednosti ne može indicirati
normalnu trudnoću ili ukazati na to koliko je vremena prošlo od začeća.
Kako bi to još bolje predočili, u sljedećoj tablici prikazane su
izmjerene prosječne vrijednosti HCG-a po danima nakon ovulacije:

dani nakon ovulacije	prosječna vrijednost HCG-a (mIU/ml)	granične vrijednosti HCG-a (mIU/ml)
14	48	17-119
15	59	17-147
16	95	33-223
17	132	17-429
18	292	70-758
19	303	111-514
20	522	135-1690
21	1061	324-4130
22	1287	185-3279
23	2034	506-4660
24	2637	540-10,000

Napomena: Vrijednosti u tablicama predstavljaju samo
okvirne prosječne vrijednosti i nisu konačni pokazatelj statusa vaše
trudnoće. O vašim rezultatima HCG testa obavezno porazgovarajte s
liječnikom.
Naime, ključ tumačenja HCG vrijednosti nije u njegovom broju, već u
njegovom rastu. U normalnoj trudnoći beta HCG raste tako da se njegova
vrijednost udvostručuje u prosjeku svaka 2 dana. Iz tog razloga, beta
HCG test se u pravilu ponavlja dva dana nakon prvog testa kako bi se
moglo vidjeti da li se «beta» pravilno «duplira». No, kako vaša
trudnoća napreduje i vrijednosti HCG-a rastu, raste i vrijeme njegova
«dupliranja»:

Vrijednost HCG-a (mIU/ml)	očekivano vrijeme «dupliranja» u satima
< 1200	48-72
1200-6000	72-96
>6000	>96

Trudnoće koje završe pobačajem ili izvanmaterične trudnoće u pravilu
pokazuju niže vrijednosti i sporije vrijeme rasta, iako i neke normalne
trudnoće, koje rezultiraju savršenim bebama, mogu također imati niže
vrijednosti HCG-a.
Nadalje, postoje mišljenja da kraće vrijeme «dupliranja» znači da su
u pitanju višeplodne trudnoće, što prema nekim istraživanjima nije
točno, mada je zapaženo da žene s višeplodnom trudnoćom imaju u pravilu
više vrijednosti HCG-a nego žene s jednoplodnom trudnoćom.
Na kraju, možemo reći da valja biti oprezan i možda ne previše
kalkulirati s brojkama. UZV pregled, nakon 5-6 tjedana, daje puno
bolje osnove za predviđanje ishoda trudnoće nego same vrijednosti HCG-a.

Ja sam i zaboravila na ovo, podsetiste me u klubu.
Pa da podignem temu malo i da dodam link teme na Rodi, gde su cure vodile svoju "statistiku"
http://forum.roda.hr/threads/54020-jo%C5%A1-jedna-statistika-kolika-bhcg-na-koji-dan-poslije-transfera